Inhibition of Aβ42 Peptide Aggregation by a Binuclear Ruthenium(II)−Platinum(II) Complex: Potential for Multimetal Organometallics as Anti-amyloid Agents

[Image: see text] Design of inhibitors for amyloid-β (Aβ) peptide aggregation has been widely investigated over the years toward developing viable therapeutic agents for Alzheimer’s disease (AD). The biggest challenge seems to be inhibiting Aβ aggregation at the early stages possibly at the monomeri...

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Main Authors: Kumar, Amit, Moody, LaMaryet, Olaivar, Jason F., Lewis, Nerissa A., Khade, Rahul L., Holder, Alvin A., Zhang, Yong, Rangachari, Vijayaraghavan
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2010
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017353/
https://ncbi.nlm.nih.gov/pubmed/21221412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn100046m
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