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Inhibition of Aβ42 Peptide Aggregation by a Binuclear Ruthenium(II)−Platinum(II) Complex: Potential for Multimetal Organometallics as Anti-amyloid Agents

[Image: see text] Design of inhibitors for amyloid-β (Aβ) peptide aggregation has been widely investigated over the years toward developing viable therapeutic agents for Alzheimer’s disease (AD). The biggest challenge seems to be inhibiting Aβ aggregation at the early stages possibly at the monomeri...

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Detalhes bibliográficos
Main Authors: Kumar, Amit, Moody, LaMaryet, Olaivar, Jason F., Lewis, Nerissa A., Khade, Rahul L., Holder, Alvin A., Zhang, Yong, Rangachari, Vijayaraghavan
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2010
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017353/
https://ncbi.nlm.nih.gov/pubmed/21221412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn100046m
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