Inhibition of Aβ42 Peptide Aggregation by a Binuclear Ruthenium(II)−Platinum(II) Complex: Potential for Multimetal Organometallics as Anti-amyloid Agents

[Image: see text] Design of inhibitors for amyloid-β (Aβ) peptide aggregation has been widely investigated over the years toward developing viable therapeutic agents for Alzheimer’s disease (AD). The biggest challenge seems to be inhibiting Aβ aggregation at the early stages possibly at the monomeri...

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מידע ביבליוגרפי
Main Authors: Kumar, Amit, Moody, LaMaryet, Olaivar, Jason F., Lewis, Nerissa A., Khade, Rahul L., Holder, Alvin A., Zhang, Yong, Rangachari, Vijayaraghavan
פורמט: Artigo
שפה:Inglês
יצא לאור: American Chemical Society 2010
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017353/
https://ncbi.nlm.nih.gov/pubmed/21221412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn100046m
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