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The splicing regulator PTBP2 is an AID interacting protein and promotes binding of AID to switch region DNA
During immunoglobulin class switch recombination (CSR), activation induced cytidine deaminase (AID) induces DNA double strand breaks into transcribed, repetitive DNA elements called switch sequences. The mechanism that promotes the binding of AID specifically to switch regions remains to be elucidat...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3724472/ https://ncbi.nlm.nih.gov/pubmed/21186367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1977 |
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