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Splicing factors PTBP1 and PTBP2 promote proliferation and migration of glioma cell lines

Polypyrimidine tract-binding protein 1 (PTBP1) is a multi-functional RNA-binding protein that is aberrantly overexpressed in glioma. PTBP1 and its brain-specific homologue polypyrimidine tract-binding protein 2 (PTBP2) regulate neural precursor cell differentiation. However, the overlapping and non-...

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Detalhes bibliográficos
Main Authors: Cheung, Hannah C., Hai, Tao, Zhu, Wen, Baggerly, Keith A., Tsavachidis, Spiridon, Krahe, Ralf, Cote, Gilbert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724917/
https://ncbi.nlm.nih.gov/pubmed/19506066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awp153
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