Erwinia asparaginase achieves therapeutic activity after pegaspargase allergy: a report from the Children’s Oncology Group

AALL07P2 evaluated whether substitution of Erwinia asparaginase 25 000 IU/m(2) for 6 doses given intramuscularly Monday/Wednesday/Friday (M/W/F) to children and young adults with acute lymphoblastic leukemia and clinical allergy to pegaspargase would provide a 48-hour nadir serum asparaginase activi...

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Detalhes bibliográficos
Main Authors: Salzer, Wanda L., Asselin, Barbara, Supko, Jeffrey G., Devidas, Meenakshi, Kaiser, Nicole A., Plourde, Paul, Winick, Naomi J., Reaman, Gregory H., Raetz, Elizabeth, Carroll, William L., Hunger, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2013
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724190/
https://ncbi.nlm.nih.gov/pubmed/23741010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-01-480822
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