Impact of Asparaginase Discontinuation on Outcome in Childhood Acute Lymphoblastic Leukemia: A Report From the Children’s Oncology Group

PURPOSE: Asparaginase (ASNase) is an important component of acute lymphoblastic leukemia (ALL) treatment, but is often discontinued because of toxicity. Erwinia chrysanthemi ASNase (Erwinia) substitution was approved in 2011 for allergic reactions. Erwinia has, however, been intermittently unavailab...

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Dettagli Bibliografici
Pubblicato in:J Clin Oncol
Autori principali: Gupta, Sumit, Wang, Cindy, Raetz, Elizabeth A., Schore, Reuven, Salzer, Wanda L., Larsen, Eric C., Maloney, Kelly W., Mattano, Len A., Carroll, William L., Winick, Naomi J., Hunger, Stephen P., Loh, Mignon L., Devidas, Meenakshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2020
Soggetti:
ORIGINAL REPORTS
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280050/
https://ncbi.nlm.nih.gov/pubmed/32275469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.03024
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