Impact of Asparaginase Discontinuation on Outcome in Childhood Acute Lymphoblastic Leukemia: A Report From the Children’s Oncology Group

PURPOSE: Asparaginase (ASNase) is an important component of acute lymphoblastic leukemia (ALL) treatment, but is often discontinued because of toxicity. Erwinia chrysanthemi ASNase (Erwinia) substitution was approved in 2011 for allergic reactions. Erwinia has, however, been intermittently unavailab...

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Veröffentlicht in:J Clin Oncol
Hauptverfasser: Gupta, Sumit, Wang, Cindy, Raetz, Elizabeth A., Schore, Reuven, Salzer, Wanda L., Larsen, Eric C., Maloney, Kelly W., Mattano, Len A., Carroll, William L., Winick, Naomi J., Hunger, Stephen P., Loh, Mignon L., Devidas, Meenakshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280050/
https://ncbi.nlm.nih.gov/pubmed/32275469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.03024
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