Impact of Asparaginase Discontinuation on Outcome in Childhood Acute Lymphoblastic Leukemia: A Report From the Children’s Oncology Group

PURPOSE: Asparaginase (ASNase) is an important component of acute lymphoblastic leukemia (ALL) treatment, but is often discontinued because of toxicity. Erwinia chrysanthemi ASNase (Erwinia) substitution was approved in 2011 for allergic reactions. Erwinia has, however, been intermittently unavailab...

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Détails bibliographiques
Publié dans:J Clin Oncol
Auteurs principaux: Gupta, Sumit, Wang, Cindy, Raetz, Elizabeth A., Schore, Reuven, Salzer, Wanda L., Larsen, Eric C., Maloney, Kelly W., Mattano, Len A., Carroll, William L., Winick, Naomi J., Hunger, Stephen P., Loh, Mignon L., Devidas, Meenakshi
Format: Artigo
Langue:Inglês
Publié: American Society of Clinical Oncology 2020
Sujets:
ORIGINAL REPORTS
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280050/
https://ncbi.nlm.nih.gov/pubmed/32275469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.03024
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