Impact of Asparaginase Discontinuation on Outcome in Childhood Acute Lymphoblastic Leukemia: A Report From the Children’s Oncology Group

PURPOSE: Asparaginase (ASNase) is an important component of acute lymphoblastic leukemia (ALL) treatment, but is often discontinued because of toxicity. Erwinia chrysanthemi ASNase (Erwinia) substitution was approved in 2011 for allergic reactions. Erwinia has, however, been intermittently unavailab...

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Bibliografiske detaljer
Udgivet i:J Clin Oncol
Main Authors: Gupta, Sumit, Wang, Cindy, Raetz, Elizabeth A., Schore, Reuven, Salzer, Wanda L., Larsen, Eric C., Maloney, Kelly W., Mattano, Len A., Carroll, William L., Winick, Naomi J., Hunger, Stephen P., Loh, Mignon L., Devidas, Meenakshi
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Clinical Oncology 2020
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ORIGINAL REPORTS
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280050/
https://ncbi.nlm.nih.gov/pubmed/32275469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.19.03024
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