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Orthosteric Binding of ρ-Da1a, a Natural Peptide of Snake Venom Interacting Selectively with the α(1A)-Adrenoceptor
ρ-Da1a is a three-finger fold toxin from green mamba venom that is highly selective for the α(1A)-adrenoceptor. This toxin has atypical pharmacological properties, including incomplete inhibition of (3)H-prazosin or (125)I-HEAT binding and insurmountable antagonist action. We aimed to clarify its mo...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3723878/ https://ncbi.nlm.nih.gov/pubmed/23935897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068841 |
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