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Photoredox Activation for the Direct β-Arylation of Ketones and Aldehydes

The direct β-activation of saturated aldehydes and ketones has long been an elusive transformation. We found that photoredox catalysis in combination with organocatalysis can lead to the transient generation of 5π-electron β-enaminyl radicals from ketones and aldehydes that rapidly couple with cyano...

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Detalhes bibliográficos
Main Authors: Pirnot, Michael T., Rankic, Danica A., Martin, David B. C., MacMillan, David W. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3723331/
https://ncbi.nlm.nih.gov/pubmed/23539600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1232993
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