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A Self-Assembling Short Oligonucleotide Duplex Suitable for Pretargeting
Monoclonal antibodies (mAbs) have naturally evolved as suitable, high affinity and specificity targeting molecules. However, the large size of full-length mAbs yields poor pharmacokinetic properties. A solution to this issue is the use of a multistep administration approach, in which the slower clea...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Mary Ann Liebert, Inc.
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3723235/ https://ncbi.nlm.nih.gov/pubmed/23848521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2013.0425 |
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