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Condensation of oligonucleotides assembled into nicked and gapped duplexes: potential structures for oligonucleotide delivery

The condensation of nucleic acids into well-defined particles is an integral part of several approaches to artificial cellular delivery. Improvements in the efficiency of nucleic acid delivery in vivo are important for the development of DNA- and RNA-based therapeutics. Presently, most efforts to im...

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Autors principals: Sarkar, Tumpa, Conwell, Christine C., Harvey, Lilia C., Santai, Catherine T., Hud, Nicholas V.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC546144/
https://ncbi.nlm.nih.gov/pubmed/15640449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki156
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