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Signaling via TLR2 and TLR4 Directly Down-Regulates T Cell Effector Functions: The Regulatory Face of Danger Signals

Toll-like receptors (TLRs) are widely expressed and play an essential role in the activation of innate immune cells. However, certain TLRs are also expressed on T cells, and TLR ligands can directly modulate T cell functions. Here, we discuss findings indicating that T cells directly respond to Heat...

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Detalhes bibliográficos
Main Authors: Zanin-Zhorov, Alexandra, Cohen, Irun R.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722573/
https://ncbi.nlm.nih.gov/pubmed/23898332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00211
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