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TLR7/TLR9- and B Cell Receptor-Signaling Crosstalk: Promotion of Potentially Dangerous B Cells

B cells are capable of receptor-mediated responses to foreign antigens. Recognition of microbial-derived nucleic acid (NA) by toll-like receptors (TLRs) 7 and 9 in B cells has been substantiated. Endogenous NA released from damaged or dying cells can also be immunogenic in certain contexts and can i...

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Pubblicato in:Front Immunol
Autori principali: Suthers, Amy N., Sarantopoulos, Stefanie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507964/
https://ncbi.nlm.nih.gov/pubmed/28751890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00775
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