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TLR signaling and effector functions are intact in XLA neutrophils
Toll-like receptors (TLRs) are essential components of the innate immune system, and their ligands are important activators of neutrophils. Bruton’s tyrosine kinase (Btk) has been reported to mediate signaling through toll-like receptors (TLRs) in many cell types, however, the role of Btk in TLR act...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941555/ https://ncbi.nlm.nih.gov/pubmed/20634142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.06.011 |
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