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TLR signaling and effector functions are intact in XLA neutrophils

Toll-like receptors (TLRs) are essential components of the innate immune system, and their ligands are important activators of neutrophils. Bruton’s tyrosine kinase (Btk) has been reported to mediate signaling through toll-like receptors (TLRs) in many cell types, however, the role of Btk in TLR act...

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Hlavní autoři: Marron, Thomas U, Rohr, Kaileen, Martinez-Gallo, Monica, Yu, Joyce, Cunningham-Rundles, Charlotte
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941555/
https://ncbi.nlm.nih.gov/pubmed/20634142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.06.011
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