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What the N-terminal domain of Atg13 looks like and what it does: A HORMA fold required for PtdIns 3-kinase recruitment

Atg13 is a subunit of the Atg1 complex that is involved in autophagy. The middle and C-terminal regions of Atg13 are intrinsically disordered and rich in regulatory phosphorylation sites. Thus far, there have been no structural data for any part of Atg13, and no function assigned to its N-terminal d...

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Detalhes bibliográficos
Main Authors: Jao, Christine C., Ragusa, Michael J., Stanley, Robin E., Hurley, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722324/
https://ncbi.nlm.nih.gov/pubmed/23670046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24896
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