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Involvement of autophagy in the response of tumor cells to PtdIns3K inhibitors: Therapeutic implications

The phosphoinositide 3-kinase (PI3K) pathway plays a crucial role in cell proliferation and survival and is frequently activated by genetic and epigenetic alterations in human cancer. An arsenal of pharmacological inhibitors of key signaling enzymes in this pathway, including class I(A) PI3K isoform...

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Hlavní autor: Arcaro, Alexandre
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627675/
https://ncbi.nlm.nih.gov/pubmed/23324613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23461
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