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The beta identity of class I PtdIns3K: A positive role of p110β in autophagy revealed

Autophagy is critically controlled by phosphatidylinositol 3-kinases (PtdIns3Ks). The common understanding for mammalian autophagy is that class I PtdIns3Ks inhibit autophagy by activating the Akt-TOR kinase cascade, whereas the class III PtdIns3K (Vps34) promotes autophagy by generating the phospho...

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Autori principali: Dou, Zhixun, Pan, Ji-An, Lin, Richard Z, Zong, Wei-Xing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359470/
https://ncbi.nlm.nih.gov/pubmed/21160279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.2.14346
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