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Involvement of autophagy in the response of tumor cells to PtdIns3K inhibitors: Therapeutic implications
The phosphoinositide 3-kinase (PI3K) pathway plays a crucial role in cell proliferation and survival and is frequently activated by genetic and epigenetic alterations in human cancer. An arsenal of pharmacological inhibitors of key signaling enzymes in this pathway, including class I(A) PI3K isoform...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627675/ https://ncbi.nlm.nih.gov/pubmed/23324613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.23461 |
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