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A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy
Autophagy-related 13 (Atg13) is a key early-acting factor in autophagy and the major locus for nutrient-dependent regulation of autophagy by Tor. The 2.3-Å resolution crystal structure of the N-terminal domain of Atg13 reveals a previously unidentified HORMA (Hop1p, Rev1p and Mad2) domain similar to...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3619307/ https://ncbi.nlm.nih.gov/pubmed/23509291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220306110 |
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