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A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy

Autophagy-related 13 (Atg13) is a key early-acting factor in autophagy and the major locus for nutrient-dependent regulation of autophagy by Tor. The 2.3-Å resolution crystal structure of the N-terminal domain of Atg13 reveals a previously unidentified HORMA (Hop1p, Rev1p and Mad2) domain similar to...

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Bibliografski detalji
Glavni autori: Jao, Christine C., Ragusa, Michael J., Stanley, Robin E., Hurley, James H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619307/
https://ncbi.nlm.nih.gov/pubmed/23509291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220306110
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