The class III phosphatidylinositol 3-kinase PIK3C3/VPS34 regulates endocytosis and autophagosome-autolysosome formation in podocytes

Phosphatidylinositol phosphates are key regulators of vesicle identity, formation and trafficking. In mammalian cells, the evolutionarily conserved class III PtdIns 3-kinase PIK3C3/VPS34 is part of a large multiprotein complex that catalyzes the localized phosphorylation of phosphatidylinositol to p...

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Autores principales: Bechtel, Wibke, Helmstädter, Martin, Balica, Jan, Hartleben, Björn, Schell, Christoph, Huber, Tobias B.
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
Materias:
Autophagic Punctum
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722319/
https://ncbi.nlm.nih.gov/pubmed/23614954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.24634
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