Vps34 Deficiency Reveals the Importance of Endocytosis for Podocyte Homeostasis

The molecular mechanisms that maintain podocytes and consequently, the integrity of the glomerular filtration barrier are incompletely understood. Here, we show that the class III phosphoinositide 3-kinase vacuolar protein sorting 34 (Vps34) plays a central role in modulating endocytic pathways, mai...

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Detalhes bibliográficos
Main Authors: Bechtel, Wibke, Helmstädter, Martin, Balica, Jan, Hartleben, Björn, Kiefer, Betina, Hrnjic, Fatima, Schell, Christoph, Kretz, Oliver, Liu, Shuya, Geist, Felix, Kerjaschki, Dontscho, Walz, Gerd, Huber, Tobias B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2013
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3636793/
https://ncbi.nlm.nih.gov/pubmed/23492732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012070700
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