Synergistic Combination Therapy with Nanoliposomal C6-Ceramide and Vinblastine is Associated with Autophagy Dysfunction in Hepatocarcinoma and Colorectal Cancer Models

Autophagy, a catabolic survival pathway, is gaining attention as a potential target in cancer. In human liver and colon cancer cells, treatment with an autophagy inducer, nanoliposomal C6-ceramide, in combination with the autophagy maturation inhibitor, vinblastine, synergistically enhanced apoptoti...

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書誌詳細
主要な著者: Adiseshaiah, Pavan P., Clogston, Jeffrey D., McLeland, Christopher B., Rodriguez, Jamie, Potter, Timothy M., Neun, Barry W., Skoczen, Sarah L., Shanmugavelandy, Sriram S., Kester, Mark, Stern, Stephan T., McNeil, Scott E.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3722309/
https://ncbi.nlm.nih.gov/pubmed/23664889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.04.034
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