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A single mutation in the core domain of the lac repressor reduces leakiness
BACKGROUND: The lac operon provides cells with the ability to switch from glucose to lactose metabolism precisely when necessary. This metabolic switch is mediated by the lac repressor (LacI), which in the absence of lactose binds to the operator DNA sequence to inhibit transcription. Allosteric rea...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3722110/ https://ncbi.nlm.nih.gov/pubmed/23834731 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-12-67 |
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