Patient survival in uveal melanoma is not affected by oncogenic mutations in GNAQ and GNA11

BACKGROUND: Mutations in GNAQ and GNA11, encoding the oncogenic G-protein alpha subunit q and 11, respectively, occur frequently in the majority of uveal melanomas. METHODS: Exons 4 and 5 from GNAQ and GNA11 were amplified and sequenced from 92 ciliary body and choroidal melanomas. The mutation stat...

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Autori principali: Koopmans, A E, Vaarwater, J, Paridaens, D, Naus, N C, Kilic, E, de Klein, A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Short Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721402/
https://ncbi.nlm.nih.gov/pubmed/23778528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.299
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