Patient survival in uveal melanoma is not affected by oncogenic mutations in GNAQ and GNA11

BACKGROUND: Mutations in GNAQ and GNA11, encoding the oncogenic G-protein alpha subunit q and 11, respectively, occur frequently in the majority of uveal melanomas. METHODS: Exons 4 and 5 from GNAQ and GNA11 were amplified and sequenced from 92 ciliary body and choroidal melanomas. The mutation stat...

詳細記述

保存先:
書誌詳細
主要な著者: Koopmans, A E, Vaarwater, J, Paridaens, D, Naus, N C, Kilic, E, de Klein, A
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2013
主題:
Short Communication
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721402/
https://ncbi.nlm.nih.gov/pubmed/23778528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.299
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