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Sprouty genes regulate proliferation and survival of human embryonic stem cells
Sprouty (Spry) genes encode negative regulators of receptor tyrosine kinase (RTK) signaling, which plays important roles in human embryonic stem cells (hESCs). SPRY2 and SPRY4 are the two most highly expressed Sprouty family members in hESCs, suggesting that they may influence self-renewal. To test...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3721083/ https://ncbi.nlm.nih.gov/pubmed/23880645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02277 |
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