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Akt3 is responsible for the survival and proliferation of embryonic stem cells

The phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB/Akt) pathway plays an important role in regulating cell proliferation, metabolism, and survival. However, the distinct roles of Akt isoforms (Akt1, Akt2, and Akt3) in pluripotent stem cell maintenance are not fully defined. Using mouse e...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Wang, Ling, Huang, Delun, Jiang, Zongliang, Luo, Yan, Norris, Carol, Zhang, Ming, Tian, Xiuchun, Tang, Young
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5483023/
https://ncbi.nlm.nih.gov/pubmed/28483982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.024505
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