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Sprouty genes regulate proliferation and survival of human embryonic stem cells

Sprouty (Spry) genes encode negative regulators of receptor tyrosine kinase (RTK) signaling, which plays important roles in human embryonic stem cells (hESCs). SPRY2 and SPRY4 are the two most highly expressed Sprouty family members in hESCs, suggesting that they may influence self-renewal. To test...

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Detalhes bibliográficos
Main Authors: Felfly, Hady, Klein, Ophir D.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721083/
https://ncbi.nlm.nih.gov/pubmed/23880645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02277
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