Novel Function of Sprouty4 as a Regulator of Stemness and Differentiation of Embryonic Stem Cells

Sprouty (Spry) genes encode inhibitors of the receptor tyrosine kinase signaling cascade, which plays important roles in stem cells. However, the role of Spry4 in the stemness of embryonic stem cells has not been fully elucidated. Here, we used mouse embryonic stem cells (mESCs) as a model system to...

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Bibliografiske detaljer
Udgivet i:Dev Reprod
Main Authors: Lee, Jae-Young, Park, Sunghyun, Kim, Kwang-Soo, Ko, Jeong-Jae, Lee, Soohong, Kim, Keun Pil, Park, Kyung-Soon
Format: Artigo
Sprog:Inglês
Udgivet: The Korean Society of Developmental Biology 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027223/
https://ncbi.nlm.nih.gov/pubmed/27660833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12717/DR.2016.20.2.171
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