A patterned recombinant human IgM guides neurite outgrowth of CNS neurons

Matrix molecules convey biochemical and physical guiding signals to neurons in the central nervous system (CNS) and shape the trajectory of neuronal fibers that constitute neural networks. We have developed recombinant human IgMs that bind to epitopes on neural cells, with the aim of treating neurol...

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Autori principali: Xu, Xiaohua, Wittenberg, Nathan J., Jordan, Luke R., Kumar, Shailabh, Watzlawik, Jens O., Warrington, Arthur E., Oh, Sang-Hyun, Rodriguez, Moses
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3721078/
https://ncbi.nlm.nih.gov/pubmed/23881231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02267
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