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p16(INK4A) Positively Regulates p21(WAF1) Expression by suppressing AUF1-dependent mRNA decay
BACKGROUND: p16(INK4a) and p21(WAF1) are two independent cyclin-dependent kinase inhibitors encoded by the CDKN2A and CDKN1A genes, respectively. p16(INK4a) and p21(WAF1) are similarly involved in various anti-cancer processes, including the regulation of the critical G1 to S phase transition of the...
Sparad:
| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3720951/ https://ncbi.nlm.nih.gov/pubmed/23894605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0070133 |
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