p16(INK4A) Positively Regulates Cyclin D1 and E2F1 through Negative Control of AUF1

BACKGROUND: The cyclin-D/CDK4,6/p16(INK4a)/pRB/E2F pathway, a key regulator of the critical G1 to S phase transition of the cell cycle, is universally disrupted in human cancer. However, the precise function of the different members of this pathway and their functional interplay are still not well d...

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Autori principali: Al-Khalaf, Huda H., Colak, Dilek, Al-Saif, Maher, Al-Bakheet, Albandary, Hendrayani, Siti-Faujiah, Al-Yousef, Nujoud, Kaya, Namik, Khabar, Khalid S., Aboussekhra, Abdelilah
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140473/
https://ncbi.nlm.nih.gov/pubmed/21799732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021111
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