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p16(INK4A) Positively Regulates Cyclin D1 and E2F1 through Negative Control of AUF1
BACKGROUND: The cyclin-D/CDK4,6/p16(INK4a)/pRB/E2F pathway, a key regulator of the critical G1 to S phase transition of the cell cycle, is universally disrupted in human cancer. However, the precise function of the different members of this pathway and their functional interplay are still not well d...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3140473/ https://ncbi.nlm.nih.gov/pubmed/21799732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021111 |
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