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p16(INK4A) enhances the transcriptional and the apoptotic functions of p53 through DNA-dependent interaction

p16(INK4A) and p53 are two important tumor suppressor proteins that play essential roles during cell proliferation and aging through regulating the expression of several genes. Here, we report that p16(INK4A) and p53 co-regulate a plethora of transcripts. Furthermore, both proteins colocalize in the...

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Bibliografiske detaljer
Udgivet i:Mol Carcinog
Main Authors: Al-Khalaf, Huda H., Nallar, Shreeram C., Kalvakolanu, Dhananjaya V., Aboussekhra, Abdelilah
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7266037/
https://ncbi.nlm.nih.gov/pubmed/28218424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22627
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