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p16(INK4A) enhances the transcriptional and the apoptotic functions of p53 through DNA-dependent interaction
p16(INK4A) and p53 are two important tumor suppressor proteins that play essential roles during cell proliferation and aging through regulating the expression of several genes. Here, we report that p16(INK4A) and p53 co-regulate a plethora of transcripts. Furthermore, both proteins colocalize in the...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Mol Carcinog |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2017
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7266037/ https://ncbi.nlm.nih.gov/pubmed/28218424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.22627 |
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