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Obesity and p16(INK4A) Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity

Obesity is increasingly recognized as a risk factor for breast cancer development. However, the molecular basis of obesity-related breast carcinogenesis remains elusive. In this study, we have shown that obesity reduces the level of the tumor suppressor p16(INK4A) protein in breast adipocytes, which...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Al-Khalaf, Huda H., Amir, Mrad, Al-Mohanna, Falah, Tulbah, Asma, Al-Sayed, Adher, Aboussekhra, Abdelilah
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5559683/
https://ncbi.nlm.nih.gov/pubmed/28630279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00101-17
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