Lysosomal association of internalized 125I-insulin in isolated rat hepatocytes. Direct demonstration by quantitative electron microscopic autoradiography.

Quantitative electron microscopic autoradiographic studies in cultured human lymphocytes and isolated rat hepatocytes have demonstrated that labeled insulin initially localizes to the plasma membrane and is subsequently internalized to a limited region of the peripheral cytoplasm. When 0.5 nm 125I-i...

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Опубликовано в::	J Clin Invest
Главные авторы:	Carpentier, J L, Gorden, P, Freychet, P, Le Cam, A, Orci, L
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Clinical Investigation 1979
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/447843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109420
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