Inhibition of prostacyclin by treatment of endothelium with aspirin. Correlation with platelet adherence.

Aspirin treatment of cultured endothelial cells from the umbilical vein increased the adherence of 51Cr-platelets when thrombin was present. If the cyclooxygenase activity of endothelium was inhibited by aspirin, as it is in the platelet, reduction of endogenous prostacyclin (PGI2) production could...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Czervionke, R L, Smith, J B, Fry, G L, Hoak, J C, Haycraft, D L
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1979
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372053/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/376548/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109379
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