Defects in DNA and globin messenger RNA in homozygotes for hemoglobin Lepore.

Globin messenger RNA (mRNA) isolated from three patients homozygous for hemoglobin Lepore is shown to have a marked reduction of the amount of beta-like globin mRNA (Lepore-globin mRNA sequences) compared with alpha-globin mRNA by molecular hybridization. The relative amounts of alpha- and Lepore mR...

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Pubblicato in:	J Clin Invest
Autori principali:	Ramirez, F, Mears, J G, Nudel, U, Bank, A, Luzzatto, L, DiPrisco, G, D'Avino, R, Pepe, G, Camardella, L, Gambino, R, Cimino, R, Quattrin, N
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1979
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372009/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/438334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109357
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