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Abnormal splice in a mutant human beta-globin gene not at the site of a mutation.

We have studied the expression of a cloned mutant human beta-globin gene in tissue culture cells. The gene, which was previously isolated from the chromosomal DNA of an individual with a low level of normal beta-globin expression (beta+-thalassemia), contains five mutations inside the large interven...

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Detalhes bibliográficos
Main Authors: Dobkin, C, Pergolizzi, R G, Bahre, P, Bank, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC393558/
https://ncbi.nlm.nih.gov/pubmed/6298782
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