Abnormal splice in a mutant human beta-globin gene not at the site of a mutation.
We have studied the expression of a cloned mutant human beta-globin gene in tissue culture cells. The gene, which was previously isolated from the chromosomal DNA of an individual with a low level of normal beta-globin expression (beta+-thalassemia), contains five mutations inside the large interven...
Guardat en:
| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1983
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393558/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6298782/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.5.1184 |
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