Abnormal splice in a mutant human beta-globin gene not at the site of a mutation.

We have studied the expression of a cloned mutant human beta-globin gene in tissue culture cells. The gene, which was previously isolated from the chromosomal DNA of an individual with a low level of normal beta-globin expression (beta+-thalassemia), contains five mutations inside the large interven...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Dobkin, C, Pergolizzi, R G, Bahre, P, Bank, A
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1983
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC393558/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6298782/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.5.1184
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