Defects in DNA and globin messenger RNA in homozygotes for hemoglobin Lepore.
Globin messenger RNA (mRNA) isolated from three patients homozygous for hemoglobin Lepore is shown to have a marked reduction of the amount of beta-like globin mRNA (Lepore-globin mRNA sequences) compared with alpha-globin mRNA by molecular hybridization. The relative amounts of alpha- and Lepore mR...
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| Publicado no: | J Clin Invest |
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| Principais autores: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1979
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC372009/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/438334/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109357 |
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