Defects in DNA and globin messenger RNA in homozygotes for hemoglobin Lepore.

Globin messenger RNA (mRNA) isolated from three patients homozygous for hemoglobin Lepore is shown to have a marked reduction of the amount of beta-like globin mRNA (Lepore-globin mRNA sequences) compared with alpha-globin mRNA by molecular hybridization. The relative amounts of alpha- and Lepore mR...

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Autores principales: Ramirez, F, Mears, J G, Nudel, U, Bank, A, Luzzatto, L, DiPrisco, G, D'Avino, R, Pepe, G, Camardella, L, Gambino, R, Cimino, R, Quattrin, N
Formato: Artigo
Lenguaje:Inglês
Publicado: 1979
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC372009/
https://ncbi.nlm.nih.gov/pubmed/438334
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