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P53 Mdm2 Inhibitors

The protein-protein interaction (PPI) between p53 and its negative regulator MDM2 comprises one of the most important and intensely studied PPI’s involved in preventing the initiation of cancer. The interaction between p53 and MDM2 is conformation-based and is tightly regulated on multiple levels. D...

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Hlavní autoři: Khoury, Kareem, Dömling, Alex
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719986/
https://ncbi.nlm.nih.gov/pubmed/22650254
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