Interleukin-7 supports survival of T-cell receptor-β-expressing CD4(−) CD8(−) double-negative thymocytes

Among the milestones that occur during T-cell development in the thymus is the expression of T-cell receptor-β (TCR-β) and the formation of the pre-TCR complex. Signals emanating from the pre-TCR trigger survival, proliferation and differentiation of T-cell precursors. Although the pre-TCR is essent...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Xiong, Juan, Parker, Brooks L, Dalheimer, Stacy L, Yankee, Thomas M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2013
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719948/
https://ncbi.nlm.nih.gov/pubmed/23215679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12050
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