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Importance of Inhibition of Binding of Complement Factor H for Serum Bactericidal Antibody Responses to Meningococcal Factor H-binding Protein Vaccines

Background. Factor H (fH) binding protein (fHbp) is part of vaccines developed for prevention of meningococcal serogroup B disease. More than 610 fHbp amino acid sequence variants have been identified, which can be classified into 2 subfamilies. The extent of cross-protection within a subfamily has...

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Hlavní autoři: Konar, Monica, Granoff, Dan M., Beernink, Peter T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719908/
https://ncbi.nlm.nih.gov/pubmed/23715659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit239
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