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Immune Mediators Regulate CFTR Expression through a Bifunctional Airway-Selective Enhancer

An airway-selective DNase-hypersensitive site (DHS) at kb −35 (DHS-35kb) 5′ to the cystic fibrosis transmembrane conductance regulator (CFTR) gene is evident in many lung cell lines and primary human tracheal epithelial cells but is absent from intestinal epithelia. The DHS-35kb contains an element...

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Hlavní autoři: Zhang, Zhaolin, Leir, Shih-Hsing, Harris, Ann
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719672/
https://ncbi.nlm.nih.gov/pubmed/23689137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00003-13
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