A transcription factor network represses CFTR gene expression in airway epithelial cells.

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene cause the inherited disorder cystic fibrosis (CF). Lung disease is the major cause of CF morbidity, though CFTR expression levels are substantially lower in the airway epithelium than in pancreatic duct and intestinal e...

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Bibliographic Details
Published in:	Biochem J
Main Authors:	Mutolo, Michael J., Leir, Shih-Hsing, Fossum, Sara L, Browne, James A, Harris, Ann
Format:	Artigo
Language:	Inglês
Published:	2018
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6380350/ https://ncbi.nlm.nih.gov/pubmed/29572268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180044
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A transcription factor network represses CFTR gene expression in airway epithelial cells.

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