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Oxidative Stress Regulates CFTR Gene Expression in Human Airway Epithelial Cells through a Distal Antioxidant Response Element

Cystic fibrosis transmembrane conductance regulator gene (CFTR) expression in human airway epithelial cells involves the recruitment of distal cis-regulatory elements, which are associated with airway-selective DNase hypersensitive sites at −44 kb and −35 kb from the gene. The −35-kb site encompasse...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Zhang, Zhaolin, Leir, Shih-Hsing, Harris, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4370264/
https://ncbi.nlm.nih.gov/pubmed/25259561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0263OC
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