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Neonatal macrophages express elevated levels of interleukin-27 that oppose immune responses

Microbial infections are a major cause of infant mortality worldwide because of impaired immune defences in this population. The nature of this work was to further understand the mechanistic limitations of the neonatal and infant immune response. Interleukin-27 (IL-27) is a heterodimeric cytokine of...

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Autori principali: Kraft, Jennifer D, Horzempa, Joseph, Davis, Celestia, Jung, Joo-Yong, Peña, Maria Marjorette O, Robinson, Cory M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719065/
https://ncbi.nlm.nih.gov/pubmed/23464355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12095
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