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Interleukin-27 inhibits phagosomal acidification by blocking vacuolar ATPases

Interleukin (IL)-27 is a unique cytokine that has a dual role in immune responses. It was originally described to promote Th1 differentiation but also suppresses inflammation by inhibiting these and other inflammatory T cell subsets. Inhibition of inflammatory activity in macrophages has also been r...

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Detalhes bibliográficos
Main Authors: Jung, Joo-Yong, Robinson, Cory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760007/
https://ncbi.nlm.nih.gov/pubmed/23557795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2013.03.010
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