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Stimulation of Endothelial Cell Prostacyclin Production by Thrombin, Trypsin, and the Ionophore A 23187

Prostacyclin (PGI(2)) is an unstable prostaglandin which inhibits platelet aggregation and serotonin release and causes vasodilation. The PGI(2) activity produced by monolayers of cultured human endothelial cells and fibroblasts was measured by the ability of their supernates to inhibit platelet agg...

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Опубликовано в::J Clin Invest
Главные авторы: Weksler, Babette B., Ley, Christopher W., Jaffe, Eric A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 1978
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371849/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/361756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109220
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